We are in relentless pursuit of breakthroughs that improve patients' lives. We innovate every day to make the world a healthier place. This was Charles Pfizer's original vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies perform better, are more creative, recruit and maintain the best professionals, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and shows our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and reflects the value we aim to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We fulfill our purpose by finding the best science in the world, working with others in the healthcare system to enhance access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can prosper.